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June 6, 2017. 2016 Annual Report: Top 10 Pipelines | PharmaLive (http://www.pharmalive.com/annual-report-top-10-pipe lines/) Biogen, Inc. (NASDAQ:BIIB) Q3 2016 Earnings Call. October 26, 2016 8:30 am ET. Executives. Matthew Calistri - Biogen, Inc. George A. Scangos - Biogen, Inc.

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June 5, 2017. Restoring What's Been Lost : National Multiple Sclerosis... (http://www.nationalmssociety.org/Research/Research- We-Fund/Restoring-What-s-Been-Lost) FirstWord Pharma PLUS is a global leader in news and intelligence for the pharmaceutical industry helping professionals stay up-to-date with the most relevant news...

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June 3, 2017. MS Research Update 2016 | MSAA: The Multiple Sclerosis... (http://mymsaa.org/publications/msresearch-update-20 16/) Biogen, Inc. (NASDAQ:BIIB) Q3 2016 Earnings Call. October 26, 2016 8:30 am ET. Executives. Matthew Calistri - Biogen, Inc. George A. Scangos - Biogen, Inc.

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June 2, 2017. Biogen (BIIB) Q3 2016 Results - Earnings Call Transcript... (https://seekingalpha.com/article/4015213-biogen-bii b-q3-2016-results-earnings-call-transcript) FirstWord Pharma PLUS is a global leader in news and intelligence for the pharmaceutical industry helping professionals stay up-to-date with the most relevant news...



May 29, 2017. Biogen (BIIB) Q3 2016 Results - Earnings Call Transcript... (https://seekingalpha.com/article/4015213-biogen-bii b-q3-2016-results-earnings-call-transcript) Mayo Clinic College of Medicine and Science; Mayo Clinic Graduate School of Biomedical Sciences; Mayo Clinic School of Medicine; Mayo Clinic School of Continuous...

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May 31, 2017. Research at Mayo Clinic - Mayo Clinic Research (http://www.mayo.edu/research/) FDA-Approved Medications. This MS Research Update 2016, covering information from the year 2015 and early 2016, must begin with a sobering note in regard to the...

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June 4, 2017. Pharma Industry News and Analysis - FirstWord Pharma (http://www.firstwordpharma.com/footer/benefits) Mayo Clinic College of Medicine and Science; Mayo Clinic Graduate School of Biomedical Sciences; Mayo Clinic School of Medicine; Mayo Clinic School of Continuous...

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June 1, 2017. Restoring What's Been Lost : National Multiple Sclerosis... (http://www.nationalmssociety.org/Research/Research- We-Fund/Restoring-What-s-Been-Lost) Mayo Clinic College of Medicine and Science; Mayo Clinic Graduate School of Biomedical Sciences; Mayo Clinic School of Medicine; Mayo Clinic School of Continuous...



May 30, 2017. 2016 Annual Report: Top 10 Pipelines | PharmaLive (http://www.pharmalive.com/annual-report-top-10-pipe lines/) FirstWord Pharma PLUS is a global leader in news and intelligence for the pharmaceutical industry helping professionals stay up-to-date with the most relevant news...

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July 9, 2017. Multiple Sclerosis Research: Remyelination on its way (http://multiple-sclerosis-research.blogspot.ca/2015 /01/remyelination-on-its-way.html) An experimental monoclonal antibody for multiple sclerosis that enhances remyelination... blocking LINGO-1 results in remyelination of CNS... (SYNERGY trial)...

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July 10, 2017. A Step Toward Multiple Sclerosis Treatment? Phase 2 ANTI... (https://multiplesclerosisnewstoday.com/2015/01/13/a -step-toward-multiple-sclerosis-treatment-phase-2-a nti-lingo-1-results-announced/) Anti-LINGO 1 Showing Promise Repairing Nerve... Anti-LINGO 1 Showing Promise Repairing Nerve Damage... et al. Evidence of Remyelination with the Anti-LINGO-1...

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July 11, 2017. SYNERGY: Anti-LINGO Agent Misses Primary Endpoint in MS (http://www.medscape.com/viewarticle/869177) Biogen has reported that its experimental treatment for relapsing forms of multiple sclerosis (MS), opicinumab (anti-LINGO-1), failed to meet its primary and...



July 12, 2017. Biogen Reports Top-Line Results from Phase 2 Study of... (http://evaluategroup.com/Universal/View.aspx?type=S tory&id=643288) Remyelination on its way... The treatment with anti-LINGO-1 appears to support some remyelination as evidenced by... In our trial just finished we had...

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July 13, 2017. ViewPoints: Data emerging (very) slowly to support... (http://firstwordpharma.com/node/1278208) Anti-LINGO-1 inhibits LINGO-1 in an effort to promote neuroprotection and remyelination in MS... Results of the trial were recently announced by Biogen Idec...

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July 14, 2017. Anti-LINGO-1 Clinical Trial Failure: A Perspective (http://www.mstranslate.com.au/anti-lingo-1-trial-fa ilure/) Opicinumab (anti-LINGO-1)... The trial was designed to detect whether treatment with opicinumab would result in... SYNERGY- opicinumab in combination with...

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July 15, 2017. Drug Successfully Restores Myelin in Phase 2 Trial | MD... (http://www.mdmag.com/medical-news/drug-successfully -restores-myelin-in-phase-2-trial-) ViewPoints: Data emerging (very) slowly to support remyelinating effects of Biogen... All-important results from the Phase II SYNERGY trial of anti-LINGO in MS...



July 16, 2017. Biogen Reports Top-Line Results from Phase 2 Study of... (http://www.businesswire.com/news/home/2016060700571 8/en/Biogen-Reports-Top-Line-Results-Phase-2-Study) What can be learnt from the failed Phase 2 clinical trial of anti-LINGO-1 for relapsing... Anti-LINGO-1 Clinical Trial Failure: A... Remyelination (which means...

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July 17, 2017. Efficacy and Safety of Anti LINGO-1 for the Treatment of... (http://www.neurology.org/content/82/10_Supplement/P 3.154.short) Drug Successfully Restores Myelin in Phase 2 Trial... Anti LINGO 1 was tested in the RENEW trial... The larger SYNERGY trial should produce results in 2016...

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July 18, 2017. Drug that boosts nerve signals offers hope for multiple... (http://www.nature.com/news/drug-that-boosts-nerve-s ignals-offers-hope-for-multiple-sclerosis-1.17367?W T.ec_id=NATURE-20150423) Efficacy and Safety of Anti LINGO-1 for the Treatment of Relapsing Forms of Multiple Sclerosis: Design of the Phase 2 SYNERGY Trial... remyelination is...

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July 19, 2017. Results Published from First Human Clinical Trials of... (http://www.nationalmssociety.org/About-the-Society/ News/Results-Published-from-First-Human-Clinical-Tr ials) Biogen's (BIIB) remyelination research includes its Phase 2 clinical trial of its anti-LINGO drug for multiple sclerosis (or MS). Data are expected by mid-2016.



July 20, 2017. BIIB033 | Multiple Sclerosis Discovery Forum (http://www.msdiscovery.org/research-resources/drug- pipeline/230-biib033) Biogen is conducting another anti-LINGO-1 trial to test an experimental way (based on magnetic resonance imaging) to assess remyelination...

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July 21, 2017. Remyelination Research for MS Could Boost Biogen's... (http://marketrealist.com/2016/02/remyelination-rese arch-program-multiple-sclerosis-expected-boost-biog ens-valuations/) Accessed on 12 Apr 2016 from http://media.biogen.com... trial to examine the efficacy of BIIB033... biogen-presents-new-anti-lingo-1-phase-2...

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July 22, 2017. Remyelination therapy goes to trial for multiple sclerosis (http://nn.neurology.org/content/1/2/e26.full) Biogen's (BIIB) remyelination research includes its Phase 2 clinical trial of its anti-LINGO drug for multiple sclerosis (or MS). Data are expected by mid-2016.

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July 23, 2017. Biogen Idec announces top-line results from anti-LINGO-1... (https://mssociety.ca/research-news/article/biogen-i dec-announces-top-line-results-from-anti-lingo-1-cl inical-trial-showing-positive-indications-of-visual -system-repair) Remyelination therapy goes to trial for... accurate methods to assess remyelination are... The anti-LINGO-1 trial is likely the first of many that will...



July 24, 2017. Biogen Presents New Anti-LINGO-1 Phase 2 Acute Optic... (http://www.businesswire.com/news/home/2015041400671 2/en/Biogen-Presents-Anti-LINGO-1-Phase-2-Acute-Opt ic) Latest MS Research News Biogen Idec announces top-line results from anti-LINGO-1 clinical trial showing positive indications of visual system repair

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July 25, 2017. Anti-LINGO-1 | Multiple Sclerosis Society UK (https://www.mssociety.org.uk/node/690821) BIOGEN PRESENTS NEW ANTI-LINGO-1 PHASE 2 ACUTE OPTIC NEURITIS DATA DEMONSTRATING NEUROLOGICAL... Remyelination with the Anti-LINGO... SYNERGY Trial...

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July 26, 2017. Phase 1 Results Reported for Anti-LINGO-1 Remyelination... (http://www.msdiscovery.org/news/new_findings/13272- phase-1-results-reported-anti-lingo-1-remyelination -agent) SYNERGY trial. This phase 2 trial... In June 2016 Biogen reported that anti-LINGO-1 had failed to improve measures of physical and cognitive function or disability.

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August 31, 2017. Biogen Idec Reports Positive Top-Line Results from Phase 2... (http://www.pipelinereview.com/index.php/20150108566 00/Antibodies/Biogen-Idec-Reports-Positive-Top-Line -Results-from-Phase-2-Anti-LINGO-1-Trial-in-People- with-Acute-Optic-Neuritis.html) Drug Successfully Restores Myelin in Phase 2 Trial... Anti LINGO 1 was tested in the RENEW trial... The larger SYNERGY trial should produce results in 2016...

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September 1, 2017. Opicinumab (anti-LINGO-1) | MS Trust (https://www.mstrust.org.uk/a-z/opicinumab-anti-ling o-1-biib033) A Step Toward Multiple Sclerosis Treatment? Read About How Phase 2 ANTI-LINGO-1 Results Were Recently... Biogen Idec expects results for the SYNERGY trial in 2016.

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September 2, 2017. P7.204 Anti-LINGO-1 Antibody for Treatment of Relapsing... (http://msneny.org/wp-content/uploads/2016/06/synerg y_aan2015poster.pdf) Biogen Idec Reports Positive Top-Line Results from Phase 2 Anti-LINGO-1 Trial in People with Acute Optic Neuritis

September 3, 2017. Biogen Idec Reports Positive Top-Line Results from Phase 2... (http://www.businesswire.com/news/home/2015010800544 6/en/Biogen-Idec-Reports-Positive-Top-Line-Results- Phase) Drug that boosts nerve signals offers hope for multiple sclerosis... Biogen is conducting another anti-LINGO-1 trial to... to assess remyelination...

September 4, 2017. Efficacy and Safety of Anti LINGO-1 for the Treatment of... (http://www.neurology.org/content/82/10_Supplement/P 3.154) An experimental monoclonal antibody for multiple sclerosis that enhances remyelination... blocking LINGO-1 results in remyelination of CNS... (SYNERGY trial)...

September 5, 2017. Drug that boosts nerve signals offers hope for multiple... (http://www.nature.com/news/drug-that-boosts-nerve-s ignals-offers-hope-for-multiple-sclerosis-1.17367) Anti-LINGO-1 inhibits LINGO-1 in an effort to promote neuroprotection and remyelination in MS... Results of the trial were recently announced by Biogen Idec...

September 6, 2017. Anti-LINGO-1 (BIIB033) Remyelination Drug... - msunites.com (http://www.msunites.com/anti-lingo-1-biib033/) Biogen's (BIIB) remyelination research includes its Phase 2 clinical trial of its anti-LINGO drug for multiple sclerosis (or MS). Data are expected by mid-2016.

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